GDP366

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.

GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.(In Vitro):GDP366 induces polyploidy in multiple types of cancer cell lines. GDP366 decreass both the mRNA and protein levels of survivin and Op18. This inhibitory effect is not dependent on the status of p53 and p21 although GDP366 potently increases p53 and p21 levels. GDP366 significantly inhibits the growth of tumor cells in vitro and in vivo (nude mouse model) without rapid induction of apoptosis.

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Others

Other Targets

Separase

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501698-03-9

375.5

C20H17N5OS

>98% (HPLC)

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Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3ncnc(N)c23)c1

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(-20℃)

With Ice Pack

≥ 2 years