Fluoromethalone ( NSC 33001 | U-8614 )

产品货号. M14448 CAS No. 426-13-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Fluoromethalone
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

氟米龙是一种皮质类固醇，最常在激光屈光手术后使用。
产品描述

Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon). Fluorometholone acetate ophthalmic suspension is indicated for use in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.(In Vitro):Fluorometholone (25-100 nM; 12 hours, 24 hours) increases the gene expression of MUC1, MUC4, MUC16 and MUC19 in the conjunctival and corneal epithelial cells through activation of glucocorticoid receptors.
体外实验

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体内实验

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同义词

NSC 33001 | U-8614
通路

Others
靶点

Other Targets
受体

Others
研究领域

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适应症

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CAS Number

426-13-1
分子量

376.46
分子式

C22H29FO4
纯度

>98% (HPLC)
溶解度

Water: 30mg/L
SMILES

CC(O[C@]1(C(C)=O)CCC2C3C[C@H](C)C4=CC(C=CC4(C)[C@@]3(F)C(O)CC12C)=O)=O
化学全称

(6S,9R,17R)-17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl acetate

1.Tong Lin, MD. Medicine (Baltimore). 2015 Feb; 94(7): 55

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