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Fluorofenidone

CAS No. 848353-85-5

Fluorofenidone ( AKF-PD )

产品货号. M26688 CAS No. 848353-85-5

Fluorofenidone attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥478 有现货
5MG ¥786 有现货
10MG ¥1320 有现货
25MG ¥2657 有现货
50MG ¥4625 有现货
100MG ¥6634 有现货
500MG ¥13689 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Fluorofenidone
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Fluorofenidone attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway.
  • 产品描述
    Fluorofenidone attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.
  • 同义词
    AKF-PD
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    848353-85-5
  • 分子量
    203.2
  • 分子式
    C12H10FNO
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cc1ccc(=O)n(c1)-c1cccc(F)c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.
产品手册
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