Faropenem

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

法罗培南是一种口服活性 β-内酰胺抗生素，对许多革兰氏阳性和革兰氏阴性需氧菌和厌氧菌具有广谱抗菌活性。

Faropenem is an orally active beta-lactam antibiotic with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes; has improved chemical stability and reduced central nervous system effects compared with imipenem.Bacterial Infection Launched.

Faropenem is not active against methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, Pseudomonas aeruginosa or Stenotrophomonas maltophilia.Faropenem is against all isolates?of?B. anthracis.?The MIC values ranged from ≤0.06 to >64 μg/liter, and the MIC90?value is 0.5 μg/ml. The MIC90?value for Faropenem is lower than that observed for other β-lactams, such as Meropenem, Amoxicillin-clavulanate, and Penicillin, for which the MIC90?values are 4 μg/ml, 4 μg/ml, and 8 μg/ml, respectively.

Faropenem ( i.p. at 24 h postchallenge at 4-, 6-, and 12-h intervals; 10, 20, 40, and 80 mg/kg/day; 14 days) demonstrates a high level of activity against B. anthracis in the murine post-exposure prophylaxis inhalation model.

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GPCR/G Protein

Antibacterial

Antibacterial

Infection

Bacterial Infection

106560-14-9

285.317

C12H15NO5S

>98% (HPLC)

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CC(C1C2N(C1=O)C(=C(S2)C3CCCO3)C(=O)O)O

(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

(-20℃)

With Ice Pack

≥ 2 years