Fantofarone ( SR 33557; SR-33557;Fantofarone )

产品货号. M17837 CAS No. 114432-13-2

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

Fantofarone
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Fantofarone is a highly potent Calcium Channel antagonist.
产品描述

Fantofarone, also known as SR 33557, is a highly potent calcium channel antagonist representative of a new class of slow channel blockers. Fantofarone can significantly modify cardiac function and in particular, decrease MO2C consumption during periods of elevated heart rate. Fantofarone is able to induce submaximal peripheral vasodilating effects at doses that are devoid of any clinically significant cardiac effect.
同义词

SR 33557; SR-33557;Fantofarone
通路

Others
靶点

Other Targets
受体

Calcium Channel
研究领域

——
适应症

——

CAS Number

114432-13-2
分子量

550.72
分子式

C31H38N2O5S
纯度

96%
溶解度

DMSO : 150 mg/mL 272.38 mM;
SMILES

COc1ccc(cc1OC)CCN(C)CCCOc2ccc(cc2)S(=O)(=O)c3c4ccccn4cc3C(C)C
化学全称

N-(3,4-dimethoxyphenethyl)-3-(4-((2-isopropylindolizin-1-yl)sulfonyl)phenoxy)-N-methylpropan-1-amine

1.Adovelande J, et al. Biochem Pharmacol. 1998 Feb 15;55(4):433-40.

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