FTIDC ( FTIDC )

产品货号. M17636 CAS No. 873551-53-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

FTIDC
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors.
产品描述

FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibition of FTIDC for mGluR1 receptors is shown to be in noncompetitive manner and displays IC50 values of 5.8 and 3.1 nM for human and mouse mGluR1 expressed in CHO cells respectively.
同义词

FTIDC
通路

Others
靶点

Other Targets
受体

mGluR1
研究领域

——
适应症

——

CAS Number

873551-53-2
分子量

358.42
分子式

C18H23FN6O
纯度

95%
溶解度

——
SMILES

C1CC(=CCN1C(=O)N(C(C)C)C)c1nnn(c1C)c1c(nccc1)F
化学全称

4-[1-(2-Fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide

1. Ito S, et al. Bioorg Med Chem. 2008 Nov 15;16(22):9817-29.

计算器

产品手册

关联产品

Aftin-4

Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor.
Sarmentosin

Sarmentosin significantly lowers the SGPT level of patients suffering from chronic viral hepatitis, and shows a suppressive effect on cell-mediated immune responses in mice.
Tamarixetin 7-O-neoh...

The herbs of Scutellaria barbata D. Don.