
FPH2
CAS No. 957485-64-2
FPH2 ( BRD-9424 )
产品货号. M17692 CAS No. 957485-64-2
FPH2 (BRD-9424) 是一种促进 iPS 衍生肝细胞分化的小分子。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥316 | 有现货 |
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10MG | ¥616 | 有现货 |
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25MG | ¥1531 | 有现货 |
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50MG | ¥2657 | 有现货 |
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100MG | ¥4690 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称FPH2
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述FPH2 (BRD-9424) 是一种促进 iPS 衍生肝细胞分化的小分子。
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产品描述FPH2 (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.
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体外实验FPH2 induces functional proliferation of hepatocytes in vitro, and thus may be useful for expanding mature human primary hepatocytes. FPH1 and FPH2 can increase in hepatocyte nuclei count and/or elevate the number of nuclei undergoing mitosis during primary screening, and these effects on hepatocytes are concentration dependent. Cells treated with FPH1 and FPH2 also maintain their liver-specific functions. Over 7 days, FPH2 induces hepatocyte doublings at a rate that is consistent with reported liver regeneration kinetics in vivo.
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体内实验——
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同义词BRD-9424
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通路MAPK/ERK Signaling
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靶点p38 MAPK
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受体Others
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研究领域Others-Field
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适应症——
化学信息
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CAS Number957485-64-2
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分子量353.83
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分子式C14H16ClN5O2S
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 125 mg/mL; 353.28 mM
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SMILESClc1cc(NC(=S)Nc2cn(nc2C(=O)N)CC)c(OC)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Shan J, et al. Nat Chem Biol. 2013, 9(8), 514-520.