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FAUC-365
CAS No. 474432-66-1
FAUC-365 ( FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide )
产品货号. M27448 CAS No. 474432-66-1
FAUC-365 is a D3 dopamine receptor agonist.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥915 | 有现货 |
|
| 10MG | ￥1393 | 有现货 |
|
| 25MG | ￥2746 | 有现货 |
|
| 50MG | ￥4358 | 有现货 |
|
| 100MG | ￥6302 | 有现货 |
|
| 500MG | ￥13122 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称FAUC-365
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述FAUC-365 is a D3 dopamine receptor agonist.
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产品描述FAUC-365 is a D3 dopamine receptor agonist.(In Vitro):As a dichloro derivative, FAUC-365 revealed D3 affinities that were comparable to its methoxy-substituted analogs, however, the selectivities of FAUC-365 against 5HT-1A, 5-HT2, and R1 were substantially higher, which was demonstrated by the extraordinary selectivity ratios of 17600, 7200, 5200, and 680 over D1, D2long, D2short, and D4, respectively, were determined for FAUC-365 with Ki of 0.50 nM. In addition, the benzothiophene analog FAUC 346 and its oxa analog showed partial agonist character with EC50 values at 0.36 and 1.5 nM, respectively .
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同义词FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide
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通路GPCR/G Protein
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靶点Dopamine Receptor
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受体LOXL2;LOXL3
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研究领域——
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适应症——
化学信息
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CAS Number474432-66-1
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分子量462.4
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分子式C23H25Cl2N3OS
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纯度>98% (HPLC)
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溶解度——
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SMILESClc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4s3)CC2)c1Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Findlay AD,et al. Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3. J Med Chem. 2019 Nov 14;62(21):9874-9889.
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