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F1324
CAS No. ——
F1324 ( —— )
产品货号. M30261 CAS No. ——
F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | 获取报价 | 有现货 |
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生物学信息
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产品名称F1324
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI.
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产品描述F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI.(In Vitro):F1324 binds to BCL6(5-129) with KD and IC50 values of 0.57 nM and 1 nM according to the results of an SPR analysis and cell-free ELISA assay, respectively. F1324 binds BCL6 not only in cell-free but also cellbased conditions.
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同义词——
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通路Others
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靶点Other Targets
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受体IC50: 1 nM (BCL6)
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量1765
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分子式C83H121N21O20S
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:Ac-{Leu}{Trp}{Tyr}{Thr}{Asp}{Ile}{Arg}{Met}{Ser}{Trp}{Arg}{Val}{Pro}-OH
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Sakamoto K, et al. Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship. Biochem Biophys Res Commun. 2017 Jan 8;482(2):310-316.
产品手册
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