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Evenamide
CAS No. 1092977-61-1
Evenamide ( NW-3509 )
产品货号. M23295 CAS No. 1092977-61-1
Evenamide 是一种钠通道阻滞剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2001 | 有现货 |
|
| 10MG | ￥3216 | 有现货 |
|
| 25MG | ￥5370 | 有现货 |
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| 50MG | ￥7655 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Evenamide
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Evenamide 是一种钠通道阻滞剂。
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产品描述Evenamide is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.
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体外实验Evenamide selectively blocks voltage-gated sodium channels (VGSCs) in a voltage-and use-dependent manner (Ki=0.4 μM) and modulates sustained repetitive firing without inducing impairment of the normal neuronal excitability. Evenamide does not bind, inhibit or interact with over 130 receptors, enzymes, or transporters.
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体内实验Evenamide is active in a wide range of psychiatric animal models in monotherapy and addon to antipsychotics. Evenamide is effective in attenuating the social interaction deficit in Cl 395 (PCP)-impaired rats (MED=1 mg/kg po).
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同义词NW-3509
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通路Membrane Transporter/Ion Channel
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靶点Sodium Channel
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受体Sodium channel
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研究领域——
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适应症——
化学信息
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CAS Number1092977-61-1
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分子量278.39
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分子式C16H26N2O2
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纯度>98% (HPLC)
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溶解度DMSO:290 mg/mL (1041.70 mM; Need ultrasonic)
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SMILESCCCCOc1cccc(CCNCC(N(C)C)=O)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Valentina Zuliani, et al. Advances in Design and Development of Sodium Channel Blockers. Ion Channels and Their Inhibitors pp 79-115.
产品手册
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