
Etimizol
CAS No. 64-99-3
Etimizol ( Ethimizole | Ethymisol | Ethymisole )
产品货号. M26209 CAS No. 64-99-3
依替咪唑被证明可以有效缓解由缺氧成分(低压缺氧、放线菌素 D、脑部机械损伤)引起的遗忘症。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥988 | 有现货 |
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10MG | ¥1596 | 有现货 |
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25MG | ¥2940 | 有现货 |
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50MG | ¥4560 | 有现货 |
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100MG | ¥6861 | 有现货 |
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200MG | ¥9153 | 有现货 |
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500MG | ¥13689 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Etimizol
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述依替咪唑被证明可以有效缓解由缺氧成分(低压缺氧、放线菌素 D、脑部机械损伤)引起的遗忘症。
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产品描述Etimizol?was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain).?(In Vivo):Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude .The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series.?Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement .?After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively .
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体外实验——
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体内实验The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series. Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement . After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively . Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude .
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同义词Ethimizole | Ethymisol | Ethymisole
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通路Others
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靶点Other Targets
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受体H1 receptor
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研究领域——
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适应症——
化学信息
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CAS Number64-99-3
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分子量210.237
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分子式C9H14N4O2
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纯度>98% (HPLC)
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溶解度In Vitro:?Ethanol : ≥ 33.33 mg/mL (158.)
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SMILESCCn1cnc(C(=O)NC)c1C(=O)NC
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Abdi A, Rose E, Levine M. Diphenhydramine overdose with intraventricular conduction delay treated with hypertonic sodium bicarbonate and i.v. lipid emulsion. West J Emerg Med. 2014 Nov;15(7):855-8.
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