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Ethoxyquin

CAS No. 91-53-2

Ethoxyquin ( NSC 6795 )

产品货号. M16574 CAS No. 91-53-2

抗氧化剂;还可以在收获后浸泡,以防止苹果和梨被烫伤。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥340 有现货
1G ¥381 有现货

生物学信息

  • 产品名称
    Ethoxyquin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    抗氧化剂;还可以在收获后浸泡,以防止苹果和梨被烫伤。
  • 产品描述
    Antioxidant; also a post-harvest dip to prevent scald on apples and pears.(In Vitro):Ethoxyquin (EQ) does not block Paclitaxel’s (PTX’s) ability to induce cell death in 4 different breast cancer cell lines. Results demonstrate that only when Hsp90 level is down regulated is neuroprotec-tion provided by Ethoxyquin (EQ) no longer seen. It is found that Ethoxyquin provides neuroprotection with a best efficacy range from 30 to 300?nM. It is interesting to note that higher (μM) concentrations of Ethoxyquin do not provide further neuroprotection and in fact at these higher concentrations Ethoxyquin loses its neuroprotective effects.(In Vivo):Ethoxyquin (EQ) provides a dose-dependent neuroprotection. Although all 3 doses of Ethoxyquin provide partial neuroprotection against reduction in intraepidermal nerve fiber density, the peak efficacy is with the 75 μg/kg dose. Rats treated with Ethoxyquin (EQ) alone or control vehicle treated rats gain weight as expected under normal physiological conditions.
  • 体外实验
    Ethoxyquin (EQ) does not block Paclitaxel’s (PTX’s) ability to induce cell death in 4 different breast cancer cell lines. Results demonstrate that only when Hsp90 level is down regulated is neuroprotec-tion provided by Ethoxyquin (EQ) no longer seen. It is found that Ethoxyquin provides neuroprotection with a best efficacy range from 30 to 300?nM. It is interesting to note that higher (μM) concentrations of Ethoxyquin do not provide further neuroprotection and in fact at these higher concentrations Ethoxyquin loses its neuroprotective effects.
  • 体内实验
    Ethoxyquin (EQ) provides a dose-dependent neuroprotection. Although all 3 doses of Ethoxyquin provide partial neuroprotection against reduction in intraepidermal nerve fiber density, the peak efficacy is with the 75 μg/kg dose. Rats treated with Ethoxyquin (EQ) alone or control vehicle treated rats gain weight as expected under normal physiological conditions.
  • 同义词
    NSC 6795
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    91-53-2
  • 分子量
    217.31
  • 分子式
    C14H19NO
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 10 mM
  • SMILES
    CC1=CC(C)(C)NC2=C1C=C(OCC)C=C2
  • 化学全称
    6-ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Rubel DM, Freeman S. Australas J Dermatol. 1998 May;39(2):89-9
产品手册
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