Eprotirome

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Eprotirome 是一种合成的甲状腺激素模拟物，是一种甲状腺激素受体激动剂。

Eprotirome a synthetic thyroid hormone mimetic is a thyroid hormone receptor agonist.(In Vivo):Eprotirome is a liver-selective thyroid hormone receptor agonist. Histological analysis of livers from mice treated with Eprotirome reveals that Eprotirome elicits a near complete elimination of lipid filled vacuoles that are characteristic of the livers from untreated control mice. Eprotirome treated mice also exhibit increased fasting glucose, but Eprotirome does not increase fasting insulin levels. Glucose levels of mice treated with Eprotirome continues to increase over time, leading to pronounced hyperglycemia by the end of the study. Temperature of mice treated with Eprotirome is decreased relative to untreated control mice.

——

Eprotirome is a liver-selective thyroid hormone receptor agonist. Histological analysis of livers from mice treated with Eprotirome reveals that Eprotirome elicits a near complete elimination of lipid filled vacuoles that are characteristic of the livers from untreated control mice. Eprotirome treated mice also exhibit increased fasting glucose, but Eprotirome does not increase fasting insulin levels. Glucose levels of mice treated with Eprotirome continues to increase over time, leading to pronounced hyperglycemia by the end of the study. Temperature of mice treated with Eprotirome is decreased relative to untreated control mice.

KB2115

Endocrinology/Hormones

THR

THR

Metabolic Disease

Dyslipidaemias; Hypercholesterolaemia; Obesity

355129-15-6

487.14

C18H17Br2NO5

>98% (HPLC)

DMSO: 90 mg/mL (184.75 mM);Ethanol: 30 mg/mL

CC(C)c1cc(Oc2c(Br)cc(NC(=O)CC(O)=O)cc2Br)ccc1O

3-((35-Dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid

(-20℃)

With Ice Pack

≥ 2 years