021-51111890
购物车（）
sales@molnova.cn
Enpp-1-IN-14
CAS No. 2687222-59-7
Enpp-1-IN-14 ( —— )
产品货号. M28549 CAS No. 2687222-59-7
ENPP1-IN-2 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥988 | 有现货 |
|
| 10MG | ￥1596 | 有现货 |
|
| 25MG | ￥3686 | 有现货 |
|
| 50MG | ￥5443 | 有现货 |
|
| 100MG | ￥7744 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Enpp-1-IN-14
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述ENPP1-IN-2 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.
-
产品描述ENPP1-IN-2 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.(In Vivo):ENPP1-IN-2 (compound 015) (50 mg/kg; IP; BID, for 31 days) significantly inhibits tumor growth in Female C57BL/6 mice (4-6 weeks; implanted subcutaneously with 2×105 MC38 cells).
-
同义词——
-
通路Angiogenesis
-
靶点PDE
-
受体KSP
-
研究领域——
-
适应症——
化学信息
-
CAS Number2687222-59-7
-
分子量403.9
-
分子式C15H22ClN5O4S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCl.O=S(=O)(N)N1CCN(C=2N=CN=C3C=C(OC)C(OC)=CC32)CCC1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Woessner R, et al. ARRY-520, a novel KSP inhibitor with potent activity in hematological and taxane-resistant tumor models. Anticancer Res. 2009 Nov;29(11):4373-80.
产品手册
关联产品
-
PF 05180999
PF-05180999 (PF 5180999) is a potent, selective, brain-penetrating and orally bioavailable phosphodiesterase 2A (PDE2A) inhibitor with IC50 of 1 nM.
-
Doxofylline
Doxofylline is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma.
-
Ibudilast
Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma.
