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Elamipretide
CAS No. 736992-21-5
Elamipretide ( SS-31 | MTP-131 | Bendavia )
产品货号. M15818 CAS No. 736992-21-5
Elamipretide (SS-31、MTP-131、Bendavia) 是一种新型细胞渗透性抗氧化剂四肽 (D-Arg-二甲基Tyr-Lys-Phe-NH2)，靶向线粒体内膜并防止神经元细胞和其他细胞类型的氧化损伤。 3期临床
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥591 | 有现货 |
|
| 5MG | ￥1077 | 有现货 |
|
| 10MG | ￥1685 | 有现货 |
|
| 25MG | ￥3038 | 有现货 |
|
| 50MG | ￥4552 | 有现货 |
|
| 100MG | ￥5824 | 有现货 |
|
| 200MG | ￥8068 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Elamipretide
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Elamipretide (SS-31、MTP-131、Bendavia) 是一种新型细胞渗透性抗氧化剂四肽 (D-Arg-二甲基Tyr-Lys-Phe-NH2)，靶向线粒体内膜并防止神经元细胞和其他细胞类型的氧化损伤。 3期临床
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产品描述Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types; prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function.Other Indication Phase 3 Clinical.
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体外实验——
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体内实验——
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同义词SS-31 | MTP-131 | Bendavia
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Other Indications
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适应症Other Disease
化学信息
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CAS Number736992-21-5
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分子量639.802
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分子式C32H49N9O5
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : ≥ 29 mg/mL (45.33 mM)
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SMILESO=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCCN)NC([C@H](CC2=C(C)C=C(O)C=C2C)NC([C@@H](CCCNC(N)=N)N)=O)=O)=O
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化学全称(S)-6-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Thomas DA, et al. J Am Soc Nephrol. 2007 Jan;18(1):213-22.
2. Zhao K, et al. Biochem Pharmacol. 2005 Dec 5;70(12):1796-806.
3. Mizuguchi Y, et al. Am J Physiol Renal Physiol. 2008 Nov;295(5):F1545-53.
产品手册
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