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ETX2514
CAS No. 1467157-21-6
ETX2514 ( ETX 2514;ETX-2514 )
产品货号. M12003 CAS No. 1467157-21-6
ETX2514 (ETX 2514, ETX-2514)is a covalent, broad-spectrum β-lactamase inhibitor with IC50 of 4, 14 and 190 nM for class A KPC-2, class C AmpC and class D OXA-24, respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥2373 | 有现货 |
|
| 5MG | ￥3629 | 有现货 |
|
| 10MG | ￥5330 | 有现货 |
|
| 25MG | ￥7995 | 有现货 |
|
| 50MG | ￥11178 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ETX2514
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ETX2514 (ETX 2514, ETX-2514)is a covalent, broad-spectrum β-lactamase inhibitor with IC50 of 4, 14 and 190 nM for class A KPC-2, class C AmpC and class D OXA-24, respectively.
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产品描述ETX2514 (ETX 2514, ETX-2514)is a covalent, broad-spectrum β-lactamase inhibitor with IC50 of 4, 14 and 190 nM for class A KPC-2, class C AmpC and class D OXA-24, respectively; potently inhibit clinically relevant class A, C and D β-lactamases and penicillin-binding proteins, resulting in intrinsic antibacterial activity against Enterobacteriaceae and restoration of β-lactam activity in a broad range of MDR Gram-negative pathogens; demonstrates potent antibacterial activity, in vivo efficacy against MDR A. baumannii infections combined with sulbactam.Bacterial Infection Phase 1 Clinical
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同义词ETX 2514;ETX-2514
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域Infection
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适应症Bacterial Infection
化学信息
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CAS Number1467157-21-6
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分子量299.23
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分子式C8H10N3NaO6S
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纯度>98% (HPLC)
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溶解度——
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SMILESCC1=CC2CN(C1C(=O)N)C(=O)N2OS(=O)(=O)[O-].[Na+]
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化学全称sodium (2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl sulfate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Durand-Réville TF, et al. Nat Microbiol. 2017 Jun 30;2:17104.
2. Shapiro AB, et al. ACS Infect Dis. 2017 Nov 10;3(11):833-844.
3. McLeod SM, et al. Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01576-17.
2. Shapiro AB, et al. ACS Infect Dis. 2017 Nov 10;3(11):833-844.
3. McLeod SM, et al. Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01576-17.
产品手册
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