ELOVL6-IN-1
CAS No. 1185736-98-4
ELOVL6-IN-1 ( —— )
产品货号. M23355 CAS No. 1185736-98-4
ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2357 | 有现货 |
|
10MG | ¥3904 | 有现货 |
|
25MG | ¥6391 | 有现货 |
|
50MG | ¥8748 | 有现货 |
|
100MG | ¥11988 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称ELOVL6-IN-1
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities.
-
产品描述ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities, with an?IC50?value of 0.350 μM. ELOVL6-IN-1 inhibits?ELOVL6?in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA[1].
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体ELOVL6
-
研究领域——
-
适应症——
化学信息
-
CAS Number1185736-98-4
-
分子量495.5
-
分子式C27H24F3N3O3
-
纯度>98% (HPLC)
-
溶解度DMSO:45 mg/mL?(90.82 mM;?Need ultrasonic)
-
SMILESO=C1N(C2=CC=CC=C2)C3=C(C(C(C)(C)CC3)=O)C1(C4=C(C)NN(C5=CC=CC=C5)C4=O)C(F)(F)F
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Shimamura K, et al. 5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological tool. J Pharmacol Exp Ther. 2009;330(1):249-256.
产品手册
关联产品
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
Azido-C6-OH
Azido-C6-OH is a cleavable ADC linker used to synthesize antibody-drug conjugates (ADCs).
-
Lophine
Lophine can be used in the synthesis of protein kinase inhibitors, calcium antagonists, strong Chemicalbook cardiac agents, and antitumor drugs.