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ELOVL6-IN-1

CAS No. 1185736-98-4

ELOVL6-IN-1 ( —— )

产品货号. M23355 CAS No. 1185736-98-4

ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2357 有现货
10MG ¥3904 有现货
25MG ¥6391 有现货
50MG ¥8748 有现货
100MG ¥11988 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    ELOVL6-IN-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities.
  • 产品描述
    ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities, with an?IC50?value of 0.350 μM. ELOVL6-IN-1 inhibits?ELOVL6?in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA[1].
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ELOVL6
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1185736-98-4
  • 分子量
    495.5
  • 分子式
    C27H24F3N3O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:45 mg/mL?(90.82 mM;?Need ultrasonic)
  • SMILES
    O=C1N(C2=CC=CC=C2)C3=C(C(C(C)(C)CC3)=O)C1(C4=C(C)NN(C5=CC=CC=C5)C4=O)C(F)(F)F
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Shimamura K, et al. 5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological tool. J Pharmacol Exp Ther. 2009;330(1):249-256.
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