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EC5026

CAS No. 1809885-32-2

EC5026 ( BPN-19186 )

产品货号. M22930 CAS No. 1809885-32-2

EC5026 has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.?EC5026 (BPN-19186) is a first-in-class, small molecule that potently inhibits soluble Epoxide Hydrolase (sEH), a key regulatory enzyme involved in the metabolism of membrane fatty acids.?Inhibition of sEH treats pain by stabilizing natural analgesic and anti-inflammatory mediators.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥389 有现货
5MG ¥624 有现货
10MG ¥1021 有现货
25MG ¥1677 有现货
50MG ¥2989 有现货
100MG ¥4447 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    EC5026
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    EC5026 has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.?EC5026 (BPN-19186) is a first-in-class, small molecule that potently inhibits soluble Epoxide Hydrolase (sEH), a key regulatory enzyme involved in the metabolism of membrane fatty acids.?Inhibition of sEH treats pain by stabilizing natural analgesic and anti-inflammatory mediators.
  • 产品描述
    EC5026 has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.?EC5026 (BPN-19186) is a first-in-class, small molecule that potently inhibits soluble Epoxide Hydrolase (sEH), a key regulatory enzyme involved in the metabolism of membrane fatty acids.?Inhibition of sEH treats pain by stabilizing natural analgesic and anti-inflammatory mediators.?sEH inhibitors developed by EicOsis have already shown efficacy for treating pain with no apparent adverse or addictive effects in laboratory animals and relieving naturally occurring pain in dogs, cats and horses.
  • 同义词
    BPN-19186
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    sEH
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1809885-32-2
  • 分子量
    405.39
  • 分子式
    C18H23F4N3O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:250 mg/mL (616.69 mM)
  • SMILES
    O=C(NC1CCN(C([C@@H](C)CC)=O)CC1)NC2=CC=C(OC(F)(F)F)C(F)=C2
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. EicOsis Announces FDA Acceptance of IND Application for EC5026, the First Soluble Epoxide Hydrolase Inhibitor to Treat Pain.2019.
产品手册
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