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E6446
CAS No. 1219925-73-1
E6446 ( E6446; E 6446; E-6446 )
产品货号. M17200 CAS No. 1219925-73-1
E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1895 | 有现货 |
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| 5MG | ￥2851 | 有现货 |
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| 10MG | ￥4253 | 有现货 |
|
| 25MG | ￥6893 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称E6446
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro.
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产品描述E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to challenge doses of cytidine-phosphate-guanidine (CpG)-containing DNA, which stimulates TLR9.
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同义词E6446; E 6446; E-6446
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通路GPCR/G Protein
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靶点Dopamine Receptor
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受体TLR7; TLR9
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number1219925-73-1
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分子量449.6
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分子式C27H35N3O3
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纯度98%
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溶解度——
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SMILESC1CCN(C1)CCCOc1ccc(cc1)c1nc2c(o1)cc(cc2)OCCCN1CCCC1
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化学全称6-(3-Pyrrolidin-1-yl-propoxy)-2-[4-(3-pyrrolidin-1-yl-propoxy)-phenyl]-benzooxazole
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1: Dias AA,et al. DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum. J Immunol. 2016 Sep 1;197(5):1905-13.
产品手册
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