Dolasetron

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Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.

HSDB 7565; HSDB7565; Dolasetron; Dolasetronum

Others

Other Targets

5-HT3

Others-Field

——

115956-12-2

324.38

C19H20N2O3

98%

DMSO : ≥ 300 mg/mL; 924.87 mM

[H][C@]12C[C@@H](C[C@@H]3C[C@H](C1)C(=O)CN23)OC(=O)c1c[nH]c2ccccc12

(6R)-3-oxooctahydro-1H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate

(-20℃)

With Ice Pack

≥ 2 years