
Dolasetron
CAS No. 115956-12-2
Dolasetron ( HSDB 7565 | HSDB7565 | Dolasetron | Dolasetronum )
产品货号. M17847 CAS No. 115956-12-2
Dolasetron (MDL-73147) 是一种血清素 5-HT3 受体拮抗剂,用于治疗化疗后的恶心和呕吐。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥356 | 有现货 |
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5MG | ¥583 | 有现货 |
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10MG | ¥883 | 有现货 |
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25MG | ¥1596 | 有现货 |
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50MG | ¥2657 | 有现货 |
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100MG | ¥3993 | 有现货 |
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500MG | ¥8667 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Dolasetron
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Dolasetron (MDL-73147) 是一种血清素 5-HT3 受体拮抗剂,用于治疗化疗后的恶心和呕吐。
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产品描述Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.
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体外实验——
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体内实验——
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同义词HSDB 7565 | HSDB7565 | Dolasetron | Dolasetronum
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通路Others
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靶点Other Targets
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受体5-HT3
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研究领域Others-Field
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适应症——
化学信息
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CAS Number115956-12-2
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分子量324.38
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分子式C19H20N2O3
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 300 mg/mL; 924.87 mM
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SMILES[H][C@]12C[C@@H](C[C@@H]3C[C@H](C1)C(=O)CN23)OC(=O)c1c[nH]c2ccccc12
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化学全称(6R)-3-oxooctahydro-1H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Faria C,etal.Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis.Am Health Drug Benefits. 2014 Jan;7(1):50-8.
产品手册




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