Digitonin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Digitonin 是从毛地黄植物紫花地黄中提取的一种甾体皂苷（saraponin）。

Digitonin is a steroidal saponin (saraponin) obtained from the foxglove plant Digitalis purpurea. It's aglycone is digitogenin, a spirostan steroid. It has been investigated as a detergent, as it effectively water-solubilizes lipids.

Digitonin, a detergent that increases cell permeability by binding to cholesterol molecules in the cell membrane, can increase cisplatin accumulation and reduce tumour growth in vitro.

In the liver parenchyma the concentrations are of the same magnitude. Measured with the 133Xe-clearance technique, Digitonin does not alter the tumor blood flow. Digitonin enhances the tumor-growth retarding effect of CBDCA given intra-aterially at 5 mg/kg but not at 25 mg/kg.

Digitin | NSC 23471 | NSC 237417

Others

Other Targets

Others

Other Indications

——

11024-24-1

1229.34

C56H92O29

>98% (HPLC)

DMSO: 10 mM

C[C@@H]1CC[C@]2(O[C@H]3[C@H]([C@H]4[C@@H]5CC[C@H]6C[C@H]([C@@H](C[C@@]6([C@H]5CC[C@@]4([C@H]3[C@@H]2C)C)C)O)O[C@@H]7O[C@@H]([C@@H]([C@@H]([C@H]7O)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O[C@@H]9O[C@@H]([C@@H]([C@@H]([C@H]9O)O[C@@H]%10O[C@@H]([C@H]([C@@H]([C@H]%10O)O)O)CO)O)CO)O[C@@H]%11OC[C@H]([C@@H]([C@H]%11O)O)O)O)CO)CO)O)OC1

beta-D-Galactopyranoside, (2alpha,3beta,5alpha,15beta,25R)-2,15-dihydroxyspirostan-3-yl O-beta-D-glucopyranosyl-(1-3)-O-beta-D-galactopyranosyl-(1-2)-O-(beta-D-xylopyranosyl-(1-3))-O-beta-D-glucopyranosyl-(1-4)-

(-20℃)

With Ice Pack

≥ 2 years