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Didymin
CAS No. 14259-47-3
Didymin ( —— )
产品货号. M18013 CAS No. 14259-47-3
Didymin 具有抗氧化特性。 Didymin 通过抑制神经母细胞瘤中的 N-Myc 和上调 RKIP 来诱导细胞凋亡，可用于神经母细胞瘤治疗。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥543 | 有现货 |
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| 10MG | ￥948 | 有现货 |
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| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Didymin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Didymin 具有抗氧化特性。 Didymin 通过抑制神经母细胞瘤中的 N-Myc 和上调 RKIP 来诱导细胞凋亡，可用于神经母细胞瘤治疗。
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产品描述Didymin has antioxidant property. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma, may used for neuroblastoma therapy. Didymin may be a potential therapeutic molecule for the treatment of neurodegenerative disorders associated with oxidative stress.
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体外实验Cell Proliferation Assay Cell Line:A549 and H460 cells Concentration:1 μM, 5 μM, 10 μM, 20 μM Incubation Time:48 h Result:Inhibited cell proliferation in human non-small-cell lung cancer cells.Apoptosis Analysis Cell Line:A549 and H460 cells Concentration:10 μM, 20 μM Incubation Time:12 h, 24 h, 48 h Result:Induced apoptosis in A549 and H460 cells, without affecting the cell cycle distribution.
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体内实验Animal Model:Male nude mice [6 weeks old; BALB/cA-nu (nu/nu)] injected with A549 cells Dosage:6 mg/kg/day Administration:i.p.; daily for 28 days Result:Inhibited tumor growth in nude mice.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number14259-47-3
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分子量594.57
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分子式C28H34O14
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 250 mg/mL (420.48 mM)
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SMILESC[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)Oc1cc(c2C(=O)C[C@H](Oc2c1)c1ccc(cc1)OC)O)O)O)O)O)O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Morelli S, et al. Neuroprotective effect of didymin on hydrogen peroxide-induced injury in the neuronal membrane system. Cells Tissues Organs. 2014;199(2-3):184-200.
