Dictamnine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

白鲜宁具有抗胆碱酯酶、抗炎、致突变作用，并对细菌和真菌具有抗菌活性。它能够对人宫颈癌、结肠癌和口腔癌细胞发挥细胞毒性。

Dictamnine shows anticholinesterase anti-inflammatory mutagenic and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix colon and oral carcinoma cells.

Western Blot Analysis Cell Line:HCT116 cells Concentration:0-100 μM Incubation Time:12 h Result:Inhibited HIF-1α (synthesis but not degradation) and Slug protein accumulation under hypoxia.

Animal Model:HCT116 xenograft tumor model Dosage:50 and 100 mg/kg Administration:p.o., three times a week Result:Inhibited tumor growth.Reduced HIF-1α and Slug protein level in the tumor tissue.

Dectamine

Microbiology/Virology

Antifection

Antifection

——

——

484-29-7

199.21

C12H9NO2

>98% (HPLC)

DMSO:50 mg/mL (250.99 mM)

COc1c2ccoc2nc2ccccc12

——

(-20℃)

With Ice Pack

≥ 2 years