021-51111890
购物车（）
sales@molnova.cn
Dianemycin
CAS No. 35865-33-9
Dianemycin ( Nanchangmycin (free acid) )
产品货号. M21964 CAS No. 35865-33-9
Dianemycin 是一种广谱聚醚抗生素，抑制革兰氏阳性菌。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥725 | 有现货 |
|
| 5MG | ￥1121 | 有现货 |
|
| 10MG | ￥1872 | 有现货 |
|
| 50MG | ￥5569 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Dianemycin
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Dianemycin 是一种广谱聚醚抗生素，抑制革兰氏阳性菌。
-
产品描述Dianemycin is a broad spectrum polyether antibiotic, inhibits gram-positive bacteria.?Nanchangmycin is a broad spectrum antiviral active against Zika virus
-
体外实验Dianemycin (Nanchangmycin) can be used as a growth promotant in poultry and to cure coccidiosis in chickens. Dianemycin is active against drug resistant strains of malaria. Dianemycin (Nanchangmycin) as a potent inhibitor of Zika virus (ZIKV) entry across all cell types tested including physiologically relevant primary cells. Dianemycin potently reduces infection of all three strains of ZIKV across all three cell types. The IC50s for infection are between 0.1 and 0.4 μM while Dianemycin has low toxicity in these ranges. In addition, DENV is inhibited by Dianemycin across cell types.
-
体内实验——
-
同义词Nanchangmycin (free acid)
-
通路GPCR/G Protein
-
靶点Antibacterial
-
受体Bacterial
-
研究领域——
-
适应症——
化学信息
-
CAS Number35865-33-9
-
分子量867.11
-
分子式C47H78O14
-
纯度>98% (HPLC)
-
溶解度DMSO:150 mg/ml(172.99 mM; Need ultrasonic)
-
SMILES[H][C@@]1(C[C@H](O[C@@H]2CC[C@H](OC)[C@@H](C)O2)[C@@H](C)[C@@]2(O[C@H](C[C@@H]2C)[C@@]2([H])O[C@@](O)(CO)[C@H](C)C[C@@H]2C)O1)[C@]1(C)CC[C@]2(C[C@H](O)[C@@H](C)[C@]([H])(O2)[C@@H](C)\C=C(/C)C(=O)[C@H](C)C[C@H](C)C(O)=O)O1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Hamill R L , Hoenh M M , Pittenger G E , et al. DIANEMYCIN, AN ANTIBIOTIC OF THE GROUP AFFECTING ION TRANSPORT[J]. The Journal of Antibiotics, 1969, 22(4):161-164.2. Rausch K, et al. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus. Cell Rep. 2017 Jan 17;18(3):804-815.3. Liu T, et al. Mechanism of thioesterase-catalyzed chain release in the biosynthesis of the polyether antibiotic Nanchangmycin. Chem Biol. 2008 May;15(5):449-58.
