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Dexrazoxane

CAS No. 24584-09-6

Dexrazoxane ( ICRF-187;NSC-169780 )

产品货号. M13714 CAS No. 24584-09-6

A derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
25MG ¥316 有现货
50MG ¥462 有现货
100MG ¥656 有现货
500MG ¥1620 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Dexrazoxane
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals.
  • 产品描述
    A derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals; protects the heart against the cardiotoxic side effects of chemotherapeutic drugs.Chemotherapeutic Agents Approved
  • 同义词
    ICRF-187;NSC-169780
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Other Targets
  • 研究领域
    Cancer
  • 适应症
    Chemotherapeutic

化学信息

  • CAS Number
    24584-09-6
  • 分子量
    268.27
  • 分子式
    C11H16N4O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    C[C@H](N(C1)CC(NC1=O)=O)CN(C2)CC(NC2=O)=O
  • 化学全称
    2,6-Piperazinedione, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Lipshultz SE, et al. N Engl J Med. 2004 Jul 8;351(2):145-53.
2. Bjelogrlic SK, et al. Exp Biol Med (Maywood). 2007 Dec;232(11):1414-24.
3. Jones RL, et al. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1311-7.
产品手册
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