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Desidustat
CAS No. 1616690-16-4
Desidustat ( —— )
产品货号. M19960 CAS No. 1616690-16-4
Desidustat 是 HIF 羟化酶的抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥389 | 有现货 |
|
| 5MG | ￥786 | 有现货 |
|
| 10MG | ￥1393 | 有现货 |
|
| 25MG | ￥2616 | 有现货 |
|
| 50MG | ￥4496 | 有现货 |
|
| 100MG | ￥6342 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Desidustat
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Desidustat 是 HIF 羟化酶的抑制剂。
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产品描述Desidustat is an inhibitor of HIF hydroxylase.(In Vivo):Desidustat (oral; 10-100 mg/kg) has good efficacy in vivo.
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体外实验——
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体内实验Desidustat (oral; 10-100 mg/kg) has good efficacy in vivo. Animal Model:C57 Mice Dosage:10, 30, 50, 100 mg/kg; 20 mg /kg Administration:oral gavage;oral, once, daily, for 7 days.Result:Significant increased the level of EPO and Hb.
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同义词——
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通路Angiogenesis
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靶点HIF/HIF Prolyl-hydroxylase
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受体HIF hydroxylase
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研究领域Cardiovascular Disease
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适应症Anaemia
化学信息
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CAS Number1616690-16-4
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分子量332.31
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分子式C16H16N2O6
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纯度>98% (HPLC)
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溶解度DMSO: 30 mg/mL
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SMILESOC(=O)CNC(=O)c1c(O)c2ccccc2n(OCC2CC2)c1=O
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化学全称N-[1-(cyclopropylmethoxy)-4-hydroxy-2-oxo- 12-dihydroquinoline-3-carbonyl]glycine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Jain M et al. Pharmacological inhibition of prolyl hydroxylase protects against inflammation-induced anemia via efficient erythropoiesis and hepcidin downregulation. Eur J Pharmacol. 2019 Jan 15;843:113-120.
