
Dermofongin
CAS No. 130-16-5
Dermofongin ( —— )
产品货号. M11211 CAS No. 130-16-5
5-氯-8-羟基喹啉,又称氯昔喹,具有抗病毒功效。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
500MG | ¥340 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Dermofongin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述5-氯-8-羟基喹啉,又称氯昔喹,具有抗病毒功效。
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产品描述5-Chloro-8-hydroxyquinoline, also called Cloxiquine, has the efficancy of anti-viral.(In Vitro):Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis.Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.(In Vivo):Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.
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体外实验Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis.Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.
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体内实验Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域Infection
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适应症——
化学信息
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CAS Number130-16-5
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分子量179.6
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分子式C9H6ClNO
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纯度>98% (HPLC)
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溶解度DMSO: 10 mM
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SMILESOC1=C2N=CC=CC2=C(Cl)C=C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Latosińska JN, et al. J Mol Model. 2011 Jul;17(7):1781-800.
产品手册




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