021-51111890
购物车（）
sales@molnova.cn
Deferasirox
CAS No. 201530-41-8
Deferasirox ( ICL670A )
产品货号. M13141 CAS No. 201530-41-8
An oral iron chelator that used to reduce chronic iron overload; also induces apoptosis in myeloid leukemia cells by targeting caspase.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥348 | 有现货 |
|
| 10MG | ￥494 | 有现货 |
|
| 25MG | ￥640 | 有现货 |
|
| 50MG | ￥964 | 有现货 |
|
| 100MG | ￥1401 | 有现货 |
|
| 500MG | ￥3475 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Deferasirox
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述An oral iron chelator that used to reduce chronic iron overload; also induces apoptosis in myeloid leukemia cells by targeting caspase.
-
产品描述An oral iron chelator that used to reduce chronic iron overload; also induces apoptosis in myeloid leukemia cells by targeting caspase.
-
同义词ICL670A
-
通路Others
-
靶点Other Targets
-
受体iron
-
研究领域Other Indications
-
适应症Other Disease
化学信息
-
CAS Number201530-41-8
-
分子量373.36
-
分子式C21H15N3O4
-
纯度>98% (HPLC)
-
溶解度10 mM in DMSO
-
SMILESO=C(O)C1=CC=C(N2N=C(C3=CC=CC=C3O)N=C2C4=CC=CC=C4O)C=C1
-
化学全称Benzoic acid, 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Sobbe A, et al. J Gastroenterol Hepatol. 2015 Mar;30(3):638-45.
2. Kim JL, et al. Acta Haematol. 2011;126(4):241-5.
3. Lee DH, et al. Exp Hematol. 2013 Jun;41(6):539-46.
2. Kim JL, et al. Acta Haematol. 2011;126(4):241-5.
3. Lee DH, et al. Exp Hematol. 2013 Jun;41(6):539-46.
产品手册
关联产品
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
Dihydrosamidin
Dihydrosamidin is a natural product. It inhibiting effect on triacylglycerol accumulation in 3T3-L1 preadipocytes.
-
PUMA BH3
PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
