DUPA

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

DUPA is used as the targeting moiety to actively deliver DTX for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer.

DUPA is used as the targeting moiety to actively deliver DTX for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer.(In Vitro):After binding to a DUPA-drug conjugate, PSMA internalizes, unloads the conjugate, and returns to the surface.(In Vivo):As determined by loss of body weight and death of treated mice,DUPA-indenoisoquinoline conjugate induces a complete cessation of tumor growth with no toxicity.

(2S,2'S)-2,2'-Carbonylbis(Azanediyl)Dipentanedioic Acid; N,N''-Carbonylbis[L-glutamic acid]

Others

Other Targets

20S proteasome

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302941-52-2

320.3

C11H16N2O9

>98% (HPLC)

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[H][C@@](CCC(O)=O)(NC(=O)N[C@@]([H])(CCC(O)=O)C(O)=O)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years