DSR-6434
CAS No. 1059070-10-8
DSR-6434 ( —— )
产品货号. M26180 CAS No. 1059070-10-8
DSR-6434 has a strong antitumor effect. DSR-6434 is a potent and selective Toll-like receptor 7 (TLR7) agonist, with EC50s of 7.2 nM and 4.6 nM for human and mice TLR7, respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥786 | 有现货 |
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10MG | ¥1337 | 有现货 |
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25MG | ¥2552 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称DSR-6434
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述DSR-6434 has a strong antitumor effect. DSR-6434 is a potent and selective Toll-like receptor 7 (TLR7) agonist, with EC50s of 7.2 nM and 4.6 nM for human and mice TLR7, respectively.
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产品描述DSR-6434 has a strong antitumor effect. DSR-6434 is a potent and selective Toll-like receptor 7 (TLR7) agonist, with EC50s of 7.2 nM and 4.6 nM for human and mice TLR7, respectively.(In Vitro):To assess the specificity of DSR-6434 toward TLR7, an NF-κB-driven reporter assay is performed in HEK293 cells engineered to express either hTLR7, TLR8 or TLR9. In this assay, successful binding of DSR-6434 to the specific receptor leads to NF-κB activation. DSR-6434 is capable of stimulating reporter gene activity only in HEK293 cells expressing hTLR7 and not in HEK293 cells expressing the structurally similar hTLR8 or hTLR9.(In Vivo):In B6C3F1 mice, DSR-6434 (0.1-1 mg/kg; i.v.) significantly suppresses lung metastasis.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number1059070-10-8
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分子量400.5
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分子式C19H28N8O2
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纯度>98% (HPLC)
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溶解度——
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SMILESCCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCN(C)C)nc3)c2n1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Goding JW. Conjugation of antibodies with fluorochromes:modifications to the standard methods. J Immunol Methods. 1976;13(3-4):215-26.
产品手册
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