DOPEXAMINE ( —— )

产品货号. M22383 CAS No. 86197-47-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

DOPEXAMINE
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Dopexamine 是一种多巴胺能激动剂，Dopexamine 盐酸盐具有有趣的血管舒张特性，对 β2 肾上腺素受体具有显着的内在激动剂活性，而对多巴胺能受体（DA1 和 DA2）具有较低的激动剂活性。
产品描述

Dopexamine is a dopaminergic agonistDopexamine hydrochloride has interesting vasodilator properties, with marked intrinsic agonist activity at beta-2 adrenoreceptors and a lesser agonist activity at dopaminergic receptors (DA1 and DA2).?Dopexamine hydrochloride is responsible for an inhibition of neuronal re-uptake of catecholamines (uptake-1), producing an indirect stimulation of cardiac beta 1-receptors.?Dopexamine hydrochloride improves cardiac performance by a marked vasodilation and a mild inotropic activity.?The specific activity at dopaminergic receptors increases cerebral, myocardial, splanchnic and renal blood flows.?These haemodynamic effects are associated with an increase in diuresis and natriuresis.?These benefits are achieved without side effects such as an increased myocardial oxygen consumption, although induced tachycardia may be responsible for chest pain/anginae pain in patients with ischaemic heart disease.
体外实验

——
体内实验

——
同义词

——
通路

GPCR/G Protein
靶点

Dopamine Receptor
受体

Dopamine
研究领域

——
适应症

——

1. Perrin G , Papazian L , Martin C . [Dopexamine: a new dopaminergic agonist].[J]. Ann Fr Anesth Reanim, 1993, 12(3):308-320.

计算器

产品手册

关联产品

Lensiprazine

Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder and schizophrenia.
SLV-310

SLV-310 is a potent dopamine D2 receptor antagonist and 5-HT reuptake receptor inhibitor used in the study of neurological disorders such as bipolar disorder and schizophrenia.
Tipepidine hydrochlo...

Tipepidine HydroHClide 是多巴胺 (DA) D2 受体介导的 GIRK 电流 (IDA(GIRK)) (IC50: 7.0 μM) 的可逆抑制剂，具有抗抑郁样作用。