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DM4

CAS No. 796073-69-3

DM4 ( Ravtansine )

产品货号. M24795 CAS No. 796073-69-3

DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥356 有现货
5MG ¥583 有现货
10MG ¥1077 有现货
25MG ¥2066 有现货
50MG ¥3629 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    DM4
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
  • 产品描述
    DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
  • 同义词
    Ravtansine
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    796073-69-3
  • 分子量
    780.4
  • 分子式
    C38H54ClN3O10S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 99 mg/mL (126.86 mM; Need ultrasonic)
  • SMILES
    CO[C@@H]1/C=C/C=C(Cc2cc(N(C(C[C@@H]([C@@]3(O[C@H]3[C@@H]([C@@H]4C[C@]1(NC(O4)=O)O)C)C)OC([C@@H](N(C(CCC(C)(S)C)=O)C)C)=O)=O)C)c(Cl)c(OC)c2)\C
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Tang R, et al. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199.
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