DM4
CAS No. 796073-69-3
DM4 ( Ravtansine )
产品货号. M24795 CAS No. 796073-69-3
DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥356 | 有现货 |
|
5MG | ¥583 | 有现货 |
|
10MG | ¥1077 | 有现货 |
|
25MG | ¥2066 | 有现货 |
|
50MG | ¥3629 | 有现货 |
|
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称DM4
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
-
产品描述DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
-
同义词Ravtansine
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域——
-
适应症——
化学信息
-
CAS Number796073-69-3
-
分子量780.4
-
分子式C38H54ClN3O10S
-
纯度>98% (HPLC)
-
溶解度DMSO: 99 mg/mL (126.86 mM; Need ultrasonic)
-
SMILESCO[C@@H]1/C=C/C=C(Cc2cc(N(C(C[C@@H]([C@@]3(O[C@H]3[C@@H]([C@@H]4C[C@]1(NC(O4)=O)O)C)C)OC([C@@H](N(C(CCC(C)(S)C)=O)C)C)=O)=O)C)c(Cl)c(OC)c2)\C
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Tang R, et al. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199.
产品手册
关联产品
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
Aristolone b
Aristolone is a natural product from the leaf oil of Alpinia polyantha.
-
PS-47
PS-47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1.