DL-Penicillamine ( —— )

产品货号. M14864 CAS No. 52-66-4

COA

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HNMR

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MSDS

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产品名称

DL-Penicillamine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

青霉素类抗生素最具特征性的降解产物。它被用作抗风湿药和威尔逊氏病的螯合剂。
产品描述

The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease. (In Vivo):DL-Penicillamine (25 mg/kg; i.p.; twice daily, for 5 days) has antidotal effects in thallotoxicosis rats when co-treated with Prussian blue (HY-106594A).
体外实验

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体内实验

DL-Penicillamine (25 mg/kg; i.p.; twice daily, for 5 days) has antidotal effects in thallotoxicosis rats when co-treated with Prussian blue (HY-106594A). Animal Model:Male Wistar rats, NIH strain (intoxicated by i.p. injection of 32 mg/kg thallium (I) acetate)Dosage:25 mg/kg Administration:i.p.; twice daily, for 5 daysResult:Decreased slightly the thallium content in blood, organs and brain.Increased the probability survival when co-treated with Prussian blue (50 mg/kg; p.o.).
同义词

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研究领域

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适应症

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1.Brewer GJ. Expert Opin PharmacOthers. 2006, 7(3):317-24

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