DFP00173

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

DFP00173 是一种有效的选择性水通道蛋白 3 (AQP3) 抑制剂。 DFP00173 抑制小鼠和人类 AQP3，IC50 约为 0.1-0.4 μM。

DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM. Compared with the homologous AQP subtypes AQP7 and AQP9, DFP00173 is selective for AQP3.(In Vitro):DFP00173 inhibits the glycerol permeability of human red blood cells with IC50 of ~0.2 μM.

DFP00173 inhibits the glycerol permeability of human erythrocytes with an IC50 of ~0.2 μM.

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Others

Other Targets

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672286-03-2

332.16

C11H7Cl2N3O3S

>98% (HPLC)

In Vitro:?DMSO : ≥ 100 mg/mL (301.06 mM)

[O-][N+](=O)c1cc(NC(=O)Nc2c(Cl)cccc2Cl)cs1

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(-20℃)

With Ice Pack

≥ 2 years