DC661 ( DC-661;DC 661 )

产品货号. M12900 CAS No. 1872387-43-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

DC661
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1).
产品描述

DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1); inhibits autophagy and causes significant impairment of tumor growth.
同义词

DC-661;DC 661
通路

Autophagy
靶点

Autophagy
受体

Autophagy
研究领域

——
适应症

——

CAS Number

1872387-43-3
分子量

550.61
分子式

C33H41Cl2N3
纯度

>98% (HPLC)
溶解度

DMSO : 62.5 mg/mL 113.11 mM;H2O : < 0.1 mg/mL
SMILES

CN(CCCCCCNC1=CC=NC2=CC(Cl)=CC=C12)CCCCCCNC3=CC=NC4=CC(Cl)=CC=C34
化学全称

N1-(6-chloronaphthalen-1-yl)-N6-(6-((6-chloronaphthalen-1-yl)amino)hexyl)-N6-methylhexane-1,6-diamine

1. Rebecca VW, et al. Cancer Discov. 2018 Nov 15. pii: CD-18-0706. doi: 10.1158/2159-8290.CD-18-0706.

计算器

产品手册

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