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D13-9001

CAS No. 957471-96-4

D13-9001 ( D 13-9001 )

产品货号. M16839 CAS No. 957471-96-4

D13-9001 (D 13-9001) is a small molecule, MexAB-OprM specific efflux pump inhibitor with good potency in vitro (MPC 2 ug/mL) and displays excellent activity in vivo in a rat pneumonia model of P. aeruginosa.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥7857 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    D13-9001
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    D13-9001 (D 13-9001) is a small molecule, MexAB-OprM specific efflux pump inhibitor with good potency in vitro (MPC 2 ug/mL) and displays excellent activity in vivo in a rat pneumonia model of P. aeruginosa.
  • 产品描述
    D13-9001 (D 13-9001) is a small molecule, MexAB-OprM specific efflux pump inhibitor with good potency in vitro (MPC 2 ug/mL) and displays excellent activity in vivo in a rat pneumonia model of P. aeruginosa.
  • 同义词
    D 13-9001
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    957471-96-4
  • 分子量
    1386.60
  • 分子式
    C63H81N22O11S2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC(C)(C)C1=CSC(=N1)NC(=O)C2=CC3=NC(=C(C(=O)N3C=C2)C=CC4=NNN=N4)N5CCCC(C5)OC(=O)NCC[N+](C)(C)CC(=O)[O-]
  • 化学全称
    Ethanaminium, N-(carboxymethyl)-2-[[[[(3R)-1-[8-[[[4-(1,1-dimethylethyl)-2-thiazolyl]amino]carbonyl]-4-oxo-3-[(1E)-2-(2H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl]-3-piperidinyl]oxy]carbonyl]amino]-N,N-dimethyl-, inner salt

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Ranjitkar S, et al. Antimicrob Agents Chemother. 2018 Nov 12. pii: AAC.01718-18. doi: 10.1128/AAC.01718-18.
2. Yoshida K, et al. Bioorg Med Chem. 2007 Nov 15;15(22):7087-97.
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