Costunolide
CAS No. 553-21-9
Costunolide ( CCRIS 6754; NSC 106404; Costus lactone; (+)-Costunolide )
产品货号. M18799 CAS No. 553-21-9
Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
纯度: 95%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥617 | 有现货 |
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10MG | ¥882 | 有现货 |
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25MG | ¥1676 | 有现货 |
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100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Costunolide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
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产品描述Costunolide, also known as (+)-Costunolide, CCRIS 6754 and NSC 106404, is a naturally occurring sesquiterpene lactone, first isolated in Saussurea costus roots in 1960. It is also found in lettuce. Costunolide has been reported for the wide spectrum of biological effects, including anti-inflammatory, anticancer, antiviral, antimicrobial, antifungal, antioxidant, antidiabetic, antiulcer, and anthelmintic activities. In recent years, it have caused extensive interest in researchers due to its potential anti-cancer activities for various types of cancer, and their anti-cancer mechanisms, including causing cell cycle arrest, inducing apoptosis and differentiation, promoting the aggregation of microtubule protein, inhibiting the activity of telomerase, inhibiting metastasis and invasion, reversing multidrug resistance, restraining angiogenesis has been studied.
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同义词CCRIS 6754; NSC 106404; Costus lactone; (+)-Costunolide
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通路Others
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靶点Other Targets
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受体FPTase; Telomerase (MCF-7); Telomerase (MDA-MB-231)
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研究领域Cancer
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适应症——
化学信息
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CAS Number553-21-9
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分子量232.32
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分子式C15H20O2
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纯度95%
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溶解度DMSO : ≥ 49 mg/mL; 210.92 mM
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SMILESO1[C@H]2[C@H](C(=C)C1=O)CC/C(=C/CC/C(=C/2)/C)/C
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化学全称(3aS,6E,10E,11aR)-6,10-dimethyl-3-methylene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Cheon YH, et al. PhytOthers Res. 2014 Apr;28(4):586-92.
产品手册
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