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Costunolide

CAS No. 553-21-9

Costunolide ( CCRIS 6754; NSC 106404; Costus lactone; (+)-Costunolide )

产品货号. M18799 CAS No. 553-21-9

Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.

纯度: 95%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥617 有现货
10MG ¥882 有现货
25MG ¥1676 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Costunolide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
  • 产品描述
    Costunolide, also known as (+)-Costunolide, CCRIS 6754 and NSC 106404, is a naturally occurring sesquiterpene lactone, first isolated in Saussurea costus roots in 1960. It is also found in lettuce. Costunolide has been reported for the wide spectrum of biological effects, including anti-inflammatory, anticancer, antiviral, antimicrobial, antifungal, antioxidant, antidiabetic, antiulcer, and anthelmintic activities. In recent years, it have caused extensive interest in researchers due to its potential anti-cancer activities for various types of cancer, and their anti-cancer mechanisms, including causing cell cycle arrest, inducing apoptosis and differentiation, promoting the aggregation of microtubule protein, inhibiting the activity of telomerase, inhibiting metastasis and invasion, reversing multidrug resistance, restraining angiogenesis has been studied.
  • 同义词
    CCRIS 6754; NSC 106404; Costus lactone; (+)-Costunolide
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    FPTase; Telomerase (MCF-7); Telomerase (MDA-MB-231)
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    553-21-9
  • 分子量
    232.32
  • 分子式
    C15H20O2
  • 纯度
    95%
  • 溶解度
    DMSO : ≥ 49 mg/mL; 210.92 mM
  • SMILES
    O1[C@H]2[C@H](C(=C)C1=O)CC/C(=C/CC/C(=C/2)/C)/C
  • 化学全称
    (3aS,6E,10E,11aR)-6,10-dimethyl-3-methylene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Cheon YH, et al. PhytOthers Res. 2014 Apr;28(4):586-92.
产品手册
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