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Clozic

CAS No. 22494-47-9

Clozic ( ICI 55897 | Clobuzarit )

产品货号. M26122 CAS No. 22494-47-9

Clozic 表现出可逆的抗增殖作用,可用于作为潜在抗关节炎药物的研究。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥9963 有现货
10MG ¥13608 有现货
25MG ¥20169 有现货
50MG ¥27216 有现货
100MG ¥36693 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Clozic
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Clozic 表现出可逆的抗增殖作用,可用于作为潜在抗关节炎药物的研究。
  • 产品描述
    Clozic exhibits reversible anti-proliferative effects and can be used in studies about serving as a potential anti-arthritic agent.(In Vitro):Clozic (>50 μM) dose-dependently decreases the amount of matrix protein synthesized by RHMC cell cultures. Clozic dose-dependently inhibits RHMC cell culture growth. Clozic (500 μM) does not affect Lactate dehydrogenase levels.
  • 体外实验
    Clozic is a potential anti-arthritic agent. Concentrations of Clozic greater than 50 μM cause a dose-dependent decrease in the amount of matrix protein synthesized by RHMC cell cultures. Inhibition of RHMC cell culture growth by Clozic occurs in a dose-dependent manner. The anti-proliferative effect of Clozic on RHMC cell growth is reversible. Lactate dehydrogenase (LDH) levels in media taken from RHMC cell cultures exposed to 500 μM Clozic for 3 days do not significantly differ from LDH levels in control cell culture media.
  • 体内实验
    ——
  • 同义词
    ICI 55897 | Clobuzarit
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    MTH1
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    22494-47-9
  • 分子量
    304.77
  • 分子式
    C17H17ClO3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC(C)(OCc1ccc(cc1)-c1ccc(Cl)cc1)C(O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.In vitro antiplasmodial activity of benzophenones and xanthones from edible fruits of Garcinia species. Planta Med. 2014 Jun;80(8-9):676-81.
产品手册
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