
Cimifugin
CAS No. 37921-38-3
Cimifugin ( Cimitin )
产品货号. M18493 CAS No. 37921-38-3
Cimifugin 抑制巨噬细胞系 RAW 264.7 中脂多糖诱导的 NO 产生,以及无细胞生物测定系统中的 1, 1-二苯基-2-三硝基苯肼自由基清除活性。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1217 | 有现货 |
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10MG | ¥2205 | 有现货 |
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25MG | ¥4322 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Cimifugin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Cimifugin 抑制巨噬细胞系 RAW 264.7 中脂多糖诱导的 NO 产生,以及无细胞生物测定系统中的 1, 1-二苯基-2-三硝基苯肼自由基清除活性。
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产品描述Cimifugin inhibits NO production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and for 1, 1-diphenyl-2-picrylhydrazyl free-radical scavenging activity in cell-free bioassay system.(In Vitro):The effect of Cimifugin (Cimitin) on TSLP decreases significantly when expression of CLDN1 is interfered with siRNA and this implied Cimifugin inhibits initiative cytokines through restoring TJs.(In Vivo):Cimifugin (Cimitin; 12.5 or 50 mg/kg/day; intragastrically; 2 days) significantly inhibits TSLP and IL-33 in the initial stage of Mice are sensitized and challenged with FITC to establish type 2 atopic dermatitis (AD) model. Simultaneously, Cimifugin reduces the separated gap among the epithelial cells and increased the expression of TJs.
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体外实验The effect of Cimifugin (Cimitin) on TSLP decreases significantly when expression of CLDN1 is interfered with siRNA and this implied Cimifugin inhibits initiative cytokines through restoring TJs.
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体内实验Cimifugin (Cimitin; 12.5 or 50 mg/kg/day; intragastrically; 2 days) significantly inhibits TSLP and IL-33 in the initial stage of Mice are sensitized and challenged with FITC to establish type 2 atopic dermatitis (AD) model. Simultaneously, Cimifugin reduces the separated gap among the epithelial cells and increased the expression of TJs.
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同义词Cimitin
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通路Others
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靶点Other Targets
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受体Others
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number37921-38-3
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分子量306.3
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分子式C16H18O6
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 3.1 mg/mL; 10.12 mM
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SMILESCC(C)([C@@H]1Cc2c(O1)cc1c(c2OC)c(=O)cc(o1)CO)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Li Y, et al. Biomed Chromatogr. 2012 Oct;26(10):1234-40.
产品手册




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