Chloroxylenol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

氯二甲酚（4-氯-3,5-二甲基苯酚）是一种广谱抗菌化合物，用于控制细菌、藻类、真菌和病毒。

Chloroxylenol (4-chloro-3,5-dimethylphenol) is a broad spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus. It is used in hospitals and households for disinfection and sanitation.

RT-PCR Cell Line:HCT116 and SW480 CRC cells Concentration:62.5-250 μM Incubation Time:24 h Result:Decreased mRNA level Axin2, Survivin and LGR5, which indicates the antagonistic effect of Chloroxylenol on the Wnt/β-catenin signaling.

Animal Model:MC38 cell xenograft modelDosage:5 mg/kg Administration:i.p., on days 0, 2, 4, 6, 8 and 10 Result:Reduced umor volume and weight.Reduced tumor cell density (H&E).Inhibited the expression of cancer stemness marker LGR5 in the tumor tissue, as well as the expression levels of LGR5 and SOX2.

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Others

Other Targets

Others

Infection

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88-04-0

156.61

C8H9ClO

>98% (HPLC)

Soluble in DMSO

CC1=CC(O)=CC(C)=C1Cl

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(-20℃)

With Ice Pack

≥ 2 years