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首页- Products - Others - Other Targets - Cefoperazone

Cefoperazone

CAS No. 62893-19-0

Cefoperazone ( Cefobid; Cefozon; T1551; T 1551 )

产品货号. M18925 CAS No. 62893-19-0

Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
200MG ￥243 有现货
500MG ￥348 有现货
1G ￥470 有现货
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生物学信息

  • 产品名称
    Cefoperazone
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
  • 产品描述
    Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. It can inhibit rMrp2-mediated [3H]E217βG uptake (IC50: 199 μM).
  • 同义词
    Cefobid; Cefozon; T1551; T 1551
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Antibacterial
  • 研究领域
    Infection
  • 适应症
    ——

化学信息

  • CAS Number
    62893-19-0
  • 分子量
    645.67
  • 分子式
    C25H27N9O8S2
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 100 mg/mL 154.88 mM H2O : < 0.1 mg/mL
  • SMILES
    [H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@H]2NC(=O)[C@H](NC(=O)N1CCN(CC)C(=O)C1=O)C1=CC=C(O)C=C1)C(O)=O
  • 化学全称
    (6R,7R)-7-((R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Kato, Y., et al., Involvement of multidrug resistance-associated protein 2 (Abcc2) in molecular weight-dependent biliary excretion of beta-lactam antibiotics. Drug Metab Dispos, 2008. 36(6): p. 1088-96.
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