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Cedirogant
CAS No. 2055496-11-0
Cedirogant ( ABBV-157 )
产品货号. M28818 CAS No. 2055496-11-0
Cedirogant 是一种口服活性视黄醇相关孤儿受体-γt(RORγt) 反向激动剂，用于银屑病研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2203 | 有现货 |
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| 10MG | ￥3507 | 有现货 |
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| 25MG | ￥5848 | 有现货 |
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| 50MG | ￥7995 | 有现货 |
|
| 100MG | ￥11178 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Cedirogant
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Cedirogant 是一种口服活性视黄醇相关孤儿受体-γt(RORγt) 反向激动剂，用于银屑病研究。
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产品描述Cedirogant is an orally active retinoid-related orphan receptor-γt(RORγt) inverse agonist that is used for psoriasis study.
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体外实验The transcription factor retinoic acid-related orphan receptor gamma t (RORγt) has been identified as the master regulator of TH17 cell differentiation and IL-17/22 production and is therefore an attractive target for the treatment of inflammatory diseases. Cedirogant (ABBV-157) has the potential for chronic plaque psoriasis research.
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体内实验——
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同义词ABBV-157
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通路Nuclear Receptor/Transcription Factor
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靶点ROR
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number2055496-11-0
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分子量547.78
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分子式C24H20Cl3F3N2O3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 250 mg/mL (456.39 mM)
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SMILESOC(CC(CC1)CCN1C(c(ccc(Cl)c1Cn(ccc2cc(C(F)(F)F)c3)c2c3Cl)c1Cl)=O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Wu Y, et al. Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair. J Biomol Screen. 2016 Jan;21(1):74-87.
