Catalpol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

梓醇是一种环烯醚萜苷，具有神经保护、抗炎和抗肝炎病毒作用。

Catalpol, an iridoid glycoside, has neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.(In Vitro):Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length.(In Vivo):Catalpol (25-100?mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities.

Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length.

Catalpol (25-100mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities. Animal Model:C57BL/6 mice treated with renal ischemia/reperfusion surgery Dosage:25 mg/kg, 50 mg/kg and 100?mg/kg Administration:Intraperitoneal injection; once Result:Clearly reduced blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal IRI mice.

Catalpinoside | 7,8-epoxy Aucubin

Others

Other Targets

Others

Other Indications

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2415-24-9

362.33

C15H22O10

>98% (HPLC)

DMSO: 10 mM

[H][C@]1([C@H](O)[C@@]2([H])[C@]3(CO)O2)[C@]3([H])[C@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)OC=C1

(2S,3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

(-20℃)

With Ice Pack

≥ 2 years