
Carbazochrome
CAS No. 69-81-8
Carbazochrome ( Carbazochrome | AC-17 | AC 17 | AC17 | Adona )
产品货号. M19012 CAS No. 69-81-8
卡唑色素是一种抗出血剂或止血剂,可通过引起血液中血小板聚集和粘附形成血小板栓来停止血流,从而阻止开放性伤口的血流。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
500MG | ¥437 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Carbazochrome
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述卡唑色素是一种抗出血剂或止血剂,可通过引起血液中血小板聚集和粘附形成血小板栓来停止血流,从而阻止开放性伤口的血流。
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产品描述Carbazochrome?is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. It is hoped that this drug can be used in the future for preventing excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on its effectiveness and the severity of possible side effects remains to be fairly inconclusive.?Carbazochrome?has been investigated for use in the treatment of hemorrhoids in a mixture with?troxerutin.(In Vitro):Carbazochrome (0.1-10 μM) inhibits the Bradykinin induced and thrombin-induced formation of [3H]IP3 in a concentration-dependent manner. Carbazochrome (0.1-1 μM), when included from 30 min before stimulation, significantly suppressed the enhancement of permeability induced by vasoactive substances.(In Vivo):Carbazochrome inhibits the severe pulmonary dysfunction induced by the intravenous injection of radiographic contrast media. Carbazochrome (1-10 mg/kg, i.v.) attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats.
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体外实验Carbazochrome (0.1-10 μM) inhibits the Bradykinin induced and thrombin-induced formation of [3H]IP3in a concentration-dependent manner.Carbazochrome (0.1-1 μM), when included from 30 min before stimulation, significantly suppressed the enhancement of permeability induced by vasoactive substances.
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体内实验Carbazochrome inhibits the severe pulmonary dysfunction induced by the intravenous injection of radiographic contrast media. Carbazochrome (1-10 mg/kg, i.v.) attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats. Animal Model:Male Sprague-Dawley rats weighing 180-230 g Dosage:10 mg/kg Administration:I.v.; injected 30, 60, or 90 min before Ioxaglate injection (4 g I/kg, i.v.).Result:Attenuated the Ioxaglate-increased vascular permeability at the dose of 1, 5 and 10 mg/kg in a dose-dependent manner, achieving statistical significance at 5 and 10 mg/kg.
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同义词Carbazochrome | AC-17 | AC 17 | AC17 | Adona
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通路Others
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靶点Other Targets
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受体myosin light-chain kinase| PLA2
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研究领域——
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适应症——
化学信息
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CAS Number69-81-8
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分子量236.23
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分子式C10H12N4O3
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 5 mg/mL (21.17 mM)
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SMILESOC1C2=C/C(=N/NC(=O)N)/C(=O)C=C2N(C1)C
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化学全称(Z)-2-(3-hydroxy-1-methyl-6-oxo-1,2,3,6-tetrahydro-5H-indol-5-ylidene)hydrazine-1-carboxamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Cecilia I, et al. Can Vet J. 2009 Aug; 50(8): 821–827.
产品手册




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