021-51111890
购物车（0）
sales@molnova.cn
Carbamazepine
CAS No. 298-46-4
Carbamazepine ( Carbamazepine, Tegretol, Epitol )
产品货号. M13912 CAS No. 298-46-4
卡马西平是一种钠通道阻滞剂，是一种抗惊厥化合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ￥300 | 有现货 |
|
| 200MG | ￥340 | 有现货 |
|
| 500MG | ￥405 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Carbamazepine
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述卡马西平是一种钠通道阻滞剂，是一种抗惊厥化合物。
-
产品描述Carbamazepine, a?sodium channel?blocker, is an anticonvulsant drug.
-
体外实验Western Blot Analysis Cell Line:3T3-L1 pre-adipocytes Concentration:0-500 μM Incubation Time:10 days Result:Decreased PPAR-γ and C/EPB-α protein levels.Increased ERK 1/2 phosphorylation after a 10?min exposure, and also increased p38 MAPK phosphorylation.
-
体内实验Animal Model:70% Partial hepatectomy treated mice Dosage:250 mg/kg Administration:p.o.Result:Recoverd liver to body weight ratio.Increased the number of BrdU-positive nuclei, Increased PCNA protein.Increased mRNA levels of ccne2 and ccna2.
-
同义词Carbamazepine, Tegretol, Epitol
-
通路Membrane Transporter/Ion Channel
-
靶点Sodium Channel
-
受体Sodium Channel
-
研究领域Neurological Disease
-
适应症——
化学信息
-
CAS Number298-46-4
-
分子量236.27
-
分子式C15H12N2O
-
纯度>98% (HPLC)
-
溶解度Ethanol: 18 mg/mL (76.18 mM); DMSO: 47 mg/mL (198.92 mM)
-
SMILESO=C(C1=CC2=CC=CC=C2NC3=CC=CC=C13)N
-
化学全称benzo[b][1]benzazepine-11-carboxamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
-
Silperisone HCl
Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperisone HCl is used to treat recurrent painful myoclonus due to spinal cord injury, abnormal hypertonia due to cerebrovascular disease, dystonia symptoms, cone tension syndrome, multiple sclerosis myospasm and myelitis. silperisone is a sodium channel protein type 2 alpha channel blocker. silperisone is an organosilicon similar to tolperisone, an organosilicon compound with centrally acting muscle relaxant properties.
-
Flecainide
一种 Ic 类抗心律失常药，用于预防和治疗快速心律失常，通过阻断心脏中的 Nav1.5 钠通道发挥作用。
-
Transcainide
Transcainide (R 54718) 是具有口服活性的抗心律失常剂。
