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Carbaglu

CAS No. 1188-38-1

Carbaglu ( Carglumic Acid )

产品货号. M10646 CAS No. 1188-38-1

Carglumic acid is an orphan drug used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and cause neurologic problems, cerebral edema, coma, and death.

纯度: >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
200MG ¥389 有现货
500MG ¥721 有现货
1G ¥964 有现货

生物学信息

  • 产品名称
    Carbaglu
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Carglumic acid is an orphan drug used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and cause neurologic problems, cerebral edema, coma, and death.
  • 产品描述
    Carglumic acid is an orphan drug used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010.
  • 同义词
    Carglumic Acid
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Carbamoyl-phosphate synthase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1188-38-1
  • 分子量
    190.15
  • 分子式
    C6H10N2O5
  • 纯度
    >98%(HPLC)
  • 溶解度
    Water: 10 mM
  • SMILES
    O=C(O)[C@@H](NC(N)=O)CCC(O)=O
  • 化学全称
    (2S)-2-(carbamoylamino)pentanedioic acid

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Carglumic acid. Prescrire Int. 2008 Apr;17(94):50-
产品手册
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