
Caracemide
CAS No. 81424-67-1
Caracemide ( NSC-253272 )
产品货号. M26639 CAS No. 81424-67-1
Caracemide 抑制大肠杆菌的核糖核苷酸还原酶。 Caracemide 可用于抗癌研究。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1037 | 有现货 |
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10MG | ¥1482 | 有现货 |
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25MG | ¥2398 | 有现货 |
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50MG | ¥3637 | 有现货 |
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100MG | ¥5338 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Caracemide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Caracemide 抑制大肠杆菌的核糖核苷酸还原酶。 Caracemide 可用于抗癌研究。
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产品描述Caracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.(In Vitro):Caracemide produces severe central nervous system (CNS) toxicity because of the toxic metabolite, methylisocyanate (MIC). Caracemide inactivates R1 by covalent modification at the substrate-binding site.(In Vivo):After administration of Caracemide (6.6 mg/kg;i.p.), the mercapturic acid derivative AMCC was identified in rats urine.
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体外实验Caracemide inactivates R1 by covalent modification at the substrate-binding site and has a toxic metabolite, methylisocyanate (MIC), in vivo.
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体内实验The mercapturic acid derivative AMCC was identified in urine rats following administration to rats of a single i.p. dose (6.6 mg/kg) of caracemide (NSC-253272). .
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同义词NSC-253272
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通路Others
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靶点Other Targets
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受体Anti-infection| Bacterial
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研究领域——
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适应症——
化学信息
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CAS Number81424-67-1
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分子量189.171
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分子式C6H11N3O4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (528.63 mM)
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SMILESCNC(=O)ON(C(C)=O)C(=O)NC
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Basanti LalHiran, et al. Oxidation of 3,4,5-trimethoxybenzaldehyde by pyridinium fluorochromate in N,N-dimethyl formamide medium: A kinetic and mechanistic study. Arabian Journal of Chemistry. Volume 9, Supplement 1, September 2016, Pages S440-S445
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