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CYP11B2-IN-1

CAS No. 1356479-78-1

CYP11B2-IN-1 ( —— )

产品货号. M26133 CAS No. 1356479-78-1

CYP11B2-IN-1 is a CYP11B2 inhibitor with IC50 of 2.3 nM. CYP11B2-IN-1 inhibits CYP11B1 with IC50 of 142 nM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥1061 有现货
5MG ¥1596 有现货
10MG ¥2535 有现货
25MG ¥4317 有现货
50MG ¥6221 有现货
100MG ¥8748 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    CYP11B2-IN-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    CYP11B2-IN-1 is a CYP11B2 inhibitor with IC50 of 2.3 nM. CYP11B2-IN-1 inhibits CYP11B1 with IC50 of 142 nM.
  • 产品描述
    CYP11B2-IN-1 is a CYP11B2 inhibitor with IC50 of 2.3 nM. CYP11B2-IN-1 inhibits CYP11B1 with IC50 of 142 nM.(In Vitro):The IC50 of CYP11B2-IN-1 for CYP19 is 1021 nM.(In Vivo):CYP11B2-IN-1 dose-dependently produces aldosterone lowering efficacy without affecting cortisol levels in rhesus pharmacodynamic models. CYP11B2-IN-1 (0.01 and 0.3 mg/kg; i.v.) reduces aldosterone AUC of 62% and 95%, respectively.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1356479-78-1
  • 分子量
    311.4
  • 分子式
    C18H18FN3O
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC(C)(O)c1cncc(c1)-c1nc2ccc(F)cc2n1C1CC1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.An Y, Zheng H, Yu Z, Sun Y, Wang Y, Zhao C, Ding W. Functioned hollow glass microsphere as a self-floating adsorbent: Rapid and high-efficient removal of anionic dye. J Hazard Mater. 2020 Jan 5;381:120971. doi: 10.1016/j.jhazmat.2019.120971. Epub 2019 Aug 10. PMID: 31421555.
产品手册
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