CTx0294885 ( CTX0294885; CTX 0294885; CTX-0294885 )

产品货号. M11865 CAS No. 1439934-41-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

CTx0294885
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

CTX-0294885 is a a novel bisanilino pyrimidine; exhibits inhibitory activity against a broad range of kinases in vitro.
产品描述

CTX-0294885 is a a novel bisanilino pyrimidine; exhibits inhibitory activity against a broad range of kinases in vitro, and further developed it into a Sepharose-supported kinase capture reagent.
同义词

CTX0294885; CTX 0294885; CTX-0294885
通路

Others
靶点

Other Targets
受体

Kinase capture reagent
研究领域

Other Indications
适应症

——

CAS Number

1439934-41-4
分子量

437.93
分子式

C22H24ClN7O
纯度

>98%(HPLC)
溶解度

DMSO: 10 mM
SMILES

O=C(NC)C1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCNCC4)C=C3)=NC=C2Cl
化学全称

2-((5-chloro-2-((4-(piperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide

1. Zhang L, et al. J Proteome Res. 2013 Jul 5;12(7):3104-16.

计算器

产品手册

关联产品

TAPI 2

ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-α from cell membranes.
Oxyresveratrol

Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis.
Methyl nomilinate

Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.