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COH34
CAS No. 906439-72-3
COH34 ( -[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol )
产品货号. M26126 CAS No. 906439-72-3
COH34 is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2341 | 有现货 |
|
| 10MG | ￥3686 | 有现货 |
|
| 25MG | ￥6099 | 有现货 |
|
| 50MG | ￥8586 | 有现货 |
|
| 100MG | ￥11583 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称COH34
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述COH34 is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.
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产品描述COH34 is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.(In Vitro):COH34 potently inhibits PARP inhibitor-resistant cancer cells.(In Vivo):COH34 shows antitumor activity in xenograft mouse cancer models.
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同义词-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol
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通路Others
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靶点Other Targets
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受体Cytidine deaminase
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研究领域——
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适应症——
化学信息
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CAS Number906439-72-3
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分子量293.4
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分子式C18H15NOS
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纯度>98% (HPLC)
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溶解度——
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SMILESCc1ccc(S\N=C\c2c(O)ccc3ccccc23)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Funamizu N, et al. Tetrahydrouridine inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels. PLoS One. 2012;7(5):e37424.
产品手册
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